The following chapter gives an overview of the semiconductor technology. Chapter 3 presents how layout data is manipulated in the VISTA TCAD framework. Chapter 4 outlines the causes of power comsumption in integrated circuits and how it can be reduced. Chapter 5 describes rigorous simulation techniques suitable for low-voltage, low-power integrated circuits. In Chapter 6 we deal with accurate three-dimensional capacitance and resistance/thermal simulations. Solid modeling techniques are presented here, as well. Several application examples of the proposed tools are presented in Chapter 7. A novel operational amplifier capable of 0.5 V power supply voltage operation is described in Chapter 8. The thesis concludes with a very brief discussion of the achieved results and gives some suggestions of future work.