Charge pumping is a transient effect in MOS devices. It represents the transfer of charge from the source and drain terminals to the bulk by transient pulses at the terminals. A DC component of the terminal currents can be measured. In this chapter advanced analytical models of the charge-pumping effect are presented. Moreover, a general two-dimensional transient numerical model of the charge-pumping effect is described. The numerical model is applied to confirm the validity of analytical models, as well as to study the cases which cannot be described by analytical approaches. At the end of the chapter charge pumping is used to analyse the degradation of MOS devices due to hot carriers.